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Publication Highlights


Knight, SP, Newman, L, O'Connor, JD, Davis, J, Kenny RA, Romero-Ortuno, R. Associations between neurocardiovascular signal entropy and physical frailty, Entropy, 2020

Associations between cardiovascular signal entropy and cognitive performance over eight years Silvin P. Knight, Louise Newman, Siobhan Scarlett, John D. O’Connor, James Davis, Celine De Looze, Rose Anne Kenny, Roman Romero-Ortuno, Entropy [Under Review]

Rizzo, R, Knight, SP, Davis, JRC, Newman, L, Duggan, E, Kenny, RA, Romero-Ortuno, R. SART and Individual Trial Mistake Thresholds: Predictive Model for Mobility Decline. Geriatrics, 6(3), 85 (2021), DOI: 10.3390/geriatrics6030085

Davis, JRC, Knight, SP, Donoghue, OA, Hernández, B, Kenny, RA, Romero-Ortuno, R. Comparison of gait speed reserve, usual gait speed, and maximum gait speed of adults aged 50+ in Ireland using explainable machine learning. medRxiv (2021) DOI: 10.1101/2021.07.23.21260911

Knight, SP, Newman, L, O’Connor, JD, Kenny, RA, Romero-Ortuno, R. Approximate entropies of resting state continuous neurocardiovascular physiological signals are associated with physical frailty in older adults. Entropy, (2021), DOI:10.3390/Entropy2021-09841

Romero-Ortuno, R, Hartley, P, Davis, J, Knight, SP, Rizzo, R, Hernández, B Kenny, RA, O’Halloran, AM. Transitions in frailty phenotype states and components over 8 years: Evidence from The Irish Longitudinal Study on Ageing Archives of Gerontology and Geriatrics, 95 (2021), DOI: 10.1016/j.archger.2021.104401

Romero-Ortuno, R, Hartley, P, Knight, SP et al. Frailty index transitions over eight years were frequent in The Irish Longitudinal Study on Ageing [version 1; peer review: 3 approved, 1 approved with reservations]. HRB Open Res 2021, 4:63 (

Moloney, D, Knight, SP, Newman, L, Kenny, RA, Romero-Ortuno, R. Eight Orthostatic Haemodynamic Patterns in The Irish Longitudinal Study on Ageing (TILDA): Stability and Clinical Associations after 4 Years. Geriatrics, (2021), DOI: 10.3390/geriatrics6020050


Knight, SP, Newman, L, O'Connor, JD, Davis, J, Kenny, RA, Romero-Ortuno, R. Associations between frailty phenotype and cardiovascular / neurovascular signal complexity, SFI Summit 2020, Virtual, Oral Presenation, 2020