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Dr. Dominic Trépel

Dominic Trepél (PhD) is Assistant Professor of Economics at TILDA and is jointly appointed to work with the Global Brain Health Institute (GBHI).

Trepél has specialised in health economics and much of this research efforts are dedicated to the study of dementia, mental health and ageing. Through his joint appointment with GBHI, he aims to exploit TILDA (and related harmonised surveys) to improve our understanding and policy response to the challenges associated with ageing, cognitive decline and dementia.

Trepél has previously held Senior Research Fellowships with leading centres in health economics including University of York and the Academic Unit for Health Economics (AUHE) at University of Leeds. His PhD examined the 'Economics of Dementia in Ireland and Europe' was supported by the prestigious Government of Ireland Scholarship (IRCHSS) and a Cochrane Fellowship (HRB), and outputs were presented to members of the Irish Parliament.

Trepél is a member of the International Health Economics Association (iHEA), and the Campbell and Cochrane Economics Methods Group (CCEMG). He was part of the scientific committee for the joint meeting of the Coèllge des Economistes de la Santé (CES) and the Health Economists' Study Group (HESG). He also peer-reviews research for the Health Economics Journal, National Institute for Health Research (NIHR), Medical Research Council (MRC) and Alzheimer's Association. He also serves on the International Panel of Scientific Advisors for the Alzheimer's Society of Ireland.

Through his international doctoral training in health economics (from the Swiss School of Public Health (SSPH+)) and from working in a number of leading research centres, Trepél offers a broad technical skillset which includes: Applied Microeconometrics, Statistical Analysis, Health Service Research, Research Design, Economic Evaluation, Cost-Effectiveness Analysis, Health Technology Assessment, Randomised Control Trials, Decision-Analytic Modelling, Health Financing, Analysis of Health Expenditures, Critical Appraisal of Decision Models, Evidence Based Medicine, Systematic Review, Meta-analysis, Medical Decision Making, Outcomes Research, Reimbursement Mechanisms and Productivity Analysis.


Postdoctoral researchers and PhDs specialising in Health Economics (or related disciplines) - interested candidates are welcome to make contact.
Health economists (and related quantitative or policy analysts) who are interested in conducting empirical research using TILDA (and/or a related datasets) in a manner that fulfil the GBHI Mission should apply for a GBHI Fellowship: - in the first instance, informal enquiries are welcomed.


  • Dominic Trepél: Cost-Effectiveness of Interventions for the Treatment of Dementia Disorders. Mental Health Economics, 08/2017: pages 339-352; , DOI:10.1007/978-3-319-55266-8_22

  • Lucilla Poston, Ruth Bell, Annette L Briley, Keith M Godfrey, Scott M Nelson, Eugene Oteng-Ntim, Jane Sandall, Thomas AB Sanders, Naveed Sattar, Paul T Seed, Stephen C Robson, Dominic Trepél, Jane Wardle: Improving pregnancy outcome in obese women: the UK Pregnancies Better Eating and Activity randomised controlled Trial. 04/2017; 5(10):1-414., DOI:10.3310/pgfar05100

  • Helen Lewis, Joy Adamson, Katie Atherton, Della Bailey, Jacqueline Birtwistle, Katharine Bosanquet, Emily Clare, Jaime Delgadillo, David Ekers, Deborah Foster, Rhian Gabe, Samantha Gascoyne, Lesley Haley, Rebecca Hargate, Catherine Hewitt, John Holmes, Ada Keding, Amanda Lilley-Kelly, Jahnese Maya, Dean McMillan, Shaista Meer, Jodi Meredith, Natasha Mitchell, Sarah Nutbrown, Karen Overend, Madeline Pasterfield, David Richards, Karen Spilsbury, David Torgerson, Gemma Traviss-Turner, Dominic Trepél, Rebecca Woodhouse, Friederike Ziegler, Simon Gilbody: CollAborative care and active surveillance for Screen-Positive EldeRs with subthreshold depression (CASPER): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness. Health technology assessment (Winchester, England) 03/2017; 21(8)., DOI:10.3310/hta21080

  • Simon Gilbody, Helen Lewis, Joy Adamson, Katie Atherton, Della Bailey, Jacqueline Birtwistle, Katharine Bosanquet, Emily Clare, Jaime Delgadillo, David Ekers, Deborah Foster, Rhian Gabe, Samantha Gascoyne, Lesley Haley, Jahnese Hamilton, Rebecca Hargate, Catherine Hewitt, John Holmes, Ada Keding, Amanda Lilley-Kelly, Shaista Meer, Natasha Mitchell, Karen Overend, Madeline Pasterfield, Jodi Pervin, David A. Richards, Karen Spilsbury, Gemma Traviss-Turner, Dominic Trepél, Rebecca Woodhouse, Friederike Ziegler, Dean McMillan: Effect of Collaborative Care vs Usual Care on Depressive Symptoms in Older Adults With Subthreshold Depression: The CASPER Randomized Clinical Trial. JAMA The Journal of the American Medical Association 02/2017; 317(7):728-737., DOI:10.1001/JAMA.2017.0130

  • Jan Illing, Paul Crampton, Charlotte Rothwell, Paul Tiffin, Dominic Trepél: What is the evidence for assuring the continuing fitness to practise of Health and Care Professions Council registrants, based on its Continuing Professional Development and audit system?. Report number: 1, DOI:10.13140/RG.2.2.29878.50241

  • Piran Cl White, Jonathan Wyatt, Garuth Chalfont, J Martin Bland, Christopher Neale, Dominic Trépel, Hilary Graham: Exposure to nature gardens has time-dependent associations with mood improvements for people with mid- and late-stage dementia: Innovative practice. Dementia 01/2017;, DOI:10.1177/1471301217723772

  • Barry Wright, Lucy Tindall, Elizabeth Littlewood, Victoria Allgar, Paul Abeles, Dominic Trepél, Shehzad Ali: Computerised cognitive-behavioural therapy for depression in adolescents: feasibility results and 4-month outcomes of a UK randomised controlled trial. BMJ Open 01/2017; 7(1)., DOI:10.1136/bmjopen-2016-012834

  • Mary Rose Sweeney, Anthony Staines, Deirdre Corby, Treasa McVeigh, Michael McKeon, Veronica Lambert, Kirsty Bowers, Edel Hoey, Andrew Boilson, Sabiha Zeynep Aydenk Koseoglu, Sarahjane Belton, Sarah Meegan, Denise Walsh, Dominic Trepél, Peter Griffin: Special Olympics Programmes Health Impact Evaluation: Main report. Report number: 1, Affiliation: Dublin City University, DOI:10.13140/RG.2.2.33080.55048

  • Denise Walsh, Sarahjane Belton, Sarah Meegan, Kirsty Bowers, Deidre Corby, Anthony Staines, Treasa McVeigh, Michael McKeon, Edel Hoey, Dominic Trepél, Peter Griffin, Mary Rose Sweeney: A comparison of physical activity, physical fitness levels, BMI and blood pressure of adults with intellectual disability, who do and do not take part in Special Olympics Ireland programmes. Journal of Intellectual Disabilities 01/2017;, DOI:10.1177/1744629516688773

  • Hayden McRobbie, Peter Hajek, Sarrah Peerbux, Katie Myers Smith, Brennan C Kahan, Sandra Eldridge, Dominic Trepél, Steve Parrott, Chris Griffiths, Sarah Snuggs. A peer-support weight management programme versus multisession advice in general practice for obese adults from deprived communities: A randomised controlled trial and economic evaluation. Health technology assessment (Winchester, England). HTA: 09/127/34. In press: October 2016.

  • Amanda E Perry, Rebecca Woodhouse, Matthew Neilson, Marrissa Martyn St James, Julie Glanville, Catherine Hewitt, Dominic Trepél: Are Non-Pharmacological Interventions Effective in Reducing Drug Use and Criminality? A Systematic and Meta-Analytical Review with an Economic Appraisal of These Interventions. International journal of environmental research and public health 09/2016; 13(10)., DOI:10.3390/ijerph13100966

  • David Marshall, Barry Wright, Victoria Allgar, Joy Adamson, Christine Williams, Hannah Ainsworth, Liz Cook, Danielle Varley, Lisa Hackney, Paul Dempster, Shehzad Ali, Dominic Trépel, Danielle Collingridge Moore, Elizabeth Littlewood, Dean McMillan: Social Stories in mainstream schools for children with autism spectrum disorder: a feasibility randomised controlled trial. BMJ Open 08/2016; 6(8-8). DOI:10.1136/bmjopen-2016-011748

  • Hoey, E., Staines, A., Walsh, D., Corby, D., Bowers, K., Belton, S., Meegan, S., McVeigh, T., McKeon, M., Trépel, D., Griffin, P., Sweeney, M.R., 07/2016. An examination of the nutritional intake and anthropometric status of individuals with intellectual disabilities: Results from the SOPHIE study. J. Intellect. Disabil. 1744629516657946. doi:10.1177/1744629516657946

  • Arri Coomarasamy, Helen Williams, Ewa Truchanowicz, Paul T Seed, Rachel Small, Siobhan Quenby, Pratima Gupta, Feroza Dawood, Yvonne E Koot, Ruth Bender Atik, Kitty Wm Bloemenkamp, Rebecca Brady, Annette Briley, Rebecca Cavallaro, Ying C Cheong, Justin Chu, Abey Eapen, Holly Essex, Ayman Ewies, Annemieke Hoek, Eugenie M Kaaijk, Carolien A Koks, Tin-Chiu Li, Marjory MacLean, Ben W Mol, Judith Moore, Steve Parrott, Jackie A Ross, Lisa Sharpe, Jane Stewart, Dominic Trepél, Nirmala Vaithilingam, Roy G Farquharson, Mark David Kilby, Yacoub Khalaf, Mariëtte Goddijn, Lesley Regan, Rajendra Rai: PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation. Health technology assessment (Winchester, England) 05/2016; 20:1-92. DOI:10.3310/hta20410

  • Barry Wright, David Marshall, Joy Adamson, Hannah Ainsworth, Shehzad Ali, Victoria Allgar, DC Moore, Elizabeth Cook, Paul Dempster, Lisa Hackney, Dean McMillan, Dominic Trepél, Chris Williams: Social Stories™ to alleviate challenging behaviour and social difficulties exhibited by children with autism spectrum disorder in mainstream schools: design of a manualised training toolkit and feasibility study for a cluster randomised controlled trial with nested qualitative and cost-effectiveness components. Health technology assessment (Winchester, England) 01/2016; 20(6). DOI:10.3310/hta20060

  • Kirsty Bowers, Deidre Corby, Veronica Lambert, Anthony Staines, Treasa McVeigh, Michael McKeon, Edel Hoey, Sarahjane Belton, Sarah Meegan, Denise Walsh, Dominic Trepél, Peter Griffin, Mary Rose Sweeney: People with intellectual disability and their families perspectives of Special Olympics Ireland: Qualitative findings from the SOPHIE study. Journal of Intellectual Disabilities 12/2015; DOI:10.1177/1744629515617059

  • Andrew Symon, Soo Downe, Kenneth William Finlayson, Rebecca Knapp, Peter Diggle, Dominic Trepél: The feasibility and acceptability of using the Mother-Generated Index (MGI) as a Patient Reported Outcome Measure in a randomised controlled trial of maternity care and SHIP trial team. BMC Medical Research Methodology 11/2015; 15(1):100. DOI:10.1186/s12874-015-0092-0 Faye Plummer, Laura Manea, Dominic Trepél, Dean McMillan: Screening for Anxiety Disorders with the GAD-7 and GAD-2: A Systematic Review and Diagnostic Meta-Analysis. General Hospital Psychiatry 11/2015; DOI:10.1016/j.genhosppsych.2015.11.005

  • Barry Wright, Melissa Barry, Ellen Hughes, Dominic Trepél, Shehzad Ali, Victoria Allgar, Lucy Cottrill, Steven Duffy, Jenny Fell, Julie Glanville, Danya Glaser, Lisa Hackney, Laura Manea, Dean McMillan, Stephen Palmer, Vivien Prior, Clare Whitton, Amanda Perry, Simon Gilbody: Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: A systematic review and meta-analysis. Health technology assessment (Winchester, England) 07/2015; 19(52):1-348. DOI:10.3310/hta19520

  • S Downe, K Finlayson, C Melvin, H Spiby, S Ali, P Diggle, G Gyte, S Hinder, V Miller, P Slade, D Trepél, A Weeks, P Whorwell, M Williamson: Self-hypnosis for intrapartum pain management in pregnant nulliparous women: A randomised controlled trial of clinical effectiveness. BJOG An International Journal of Obstetrics & Gynaecology 05/2015; 122(9):n/a. DOI:10.1111/1471-0528.13433 Dominic Trepél, Margaret Crean, Emer Bedley: An Economic Analysis of Home Care Services for People with Dementia. Alzheimer Society of Ireland, Dublin. 2015

  • Rachel Richardson, Dominic Trepél, Amanda Perry, Shehzad Ali, Steven Duffy, Rhian Gabe, Simon Gilbody, Julie Glanville, Catherine Hewitt, Laura Manea, Stephen Palmer, Barry Wright, Dean McMillan: Screening for psychological and mental health difficulties in young people who offend: A systematic review and decision model. Health technology assessment (Winchester, England) 01/2015; 19. DOI:10.3310/hta19010

  • Karen Overend, Helen Lewis, Della Bailey, Kate Bosanquet, Carolyn Chew-Graham, David Ekers, Samantha Gascoyne, Deborah Hems, John Holmes, Ada Keding, Dean McMillan, Shaista Meer, Natasha Mitchell, Sarah Nutbrown, Steve Parrott, David Richards, Gemma Traviss, Dominic Trepél, Rebecca Woodhouse, Simon Gilbody: CASPER plus (CollAborative care in Screen-Positive EldeRs with major depressive disorder): Study protocol for a randomised controlled trial. Trials 11/2014; 15(1):451. DOI:10.1186/1745-6215-15-451

  • Barry Wright, Lucy Tindall, Elizabeth Littlewood, Joy Adamson, Victoria Allgar, Sophie Bennett, Simon Gilbody, Chrissie Verduyn, Ben Alderson-Day, Lisa Dyson, Dominic Trepél, Shehzad Ali: Computerised cognitive behaviour therapy for depression in adolescents: Study protocol for a feasibility randomised controlled trial. BMJ Open 10/2014; 4(10):e006488. DOI:10.1136/bmjopen-2014-006488

  • Barry Wright, David Marshall, Danielle Collingridge Moore, Hannah Ainsworth, Lisa Hackney, Joy Adamson, Shehzad Ali, Victoria Allgar, Liz Cook, Lisa Dyson, Elizabeth Littlewood, Rebecca Hargate, Anne McLaren, Dean McMillan, Dominic Trepél, Jo Whitehead, Chris Williams: Autism Spectrum Social Stories In Schools Trial (ASSSIST): study protocol for a feasibility randomised controlled trial analysing clinical and cost-effectiveness of Social Stories in mainstream schools. BMJ Open 07/2014; 4(7):e005952. DOI:10.1136/bmjopen-2014-005952

  • B Fenn, D Trepél, C Dolan, J Shoham, V Sibson: Seasonal unconditional cash transfers and wasting in Niger. Annals of Nutrition and Metabolism 01/2013; 63:1002.

  • Dominic Trepél: Expert Policy Paper Series 2012 Financing Dementia What money is available, what does dementia need and will the required resources be received?. Report number: Expert Policy Paper Series 2012, Affiliation: The Alzheimer Society of Ireland. 2012

  • D Trepél: An update on the economics of dementia care in Ireland. Irish medical journal 02/2012; 105(2):38-9. Dominic Trepél: Informal Cost of Dementia Care - A Proxy-Good Valuation in Ireland. The Economic and social review 08/2011; 42(4):479-503.

  • Dominic Trepél: An Economic Perspective of Dementia Care in Ireland. Affiliation: Alzheimer Society of Ireland, Dublin, Ireland. 2010

  • Dominic Trepél: An Economic Perspective of Dementia Care in Ireland 1 Executive Summary. Report number: Policy Paper 1, Affiliation: Alzheimer Society of Ireland. 2010