Dr. Céline De Looze
Céline De Looze is a research fellow in cognitive neuroscience. She is the lead of the Cognitive Neuroscience and MRI research groups in TILDA. She joined TILDA in 2018. Her research aims to investigate the risk and protective factors associated with cardiovascular, brain and cognitive health in a multi-system perspective. Focused on the heart-brain axis, she examines the effects of behavioural factors (e.g. chronic stress, sleep) on the cardiovascular system and the brain. She investigates how the cardiovascular system and the brain interact with each other and respond to these stressors, and examines the cascade of these effects on cognitive trajectories in older age. Her research interests also include the study of behavioural measures for the monitoring of cognitive function, with a focus on developing quantitative methods for the analysis of speech, association with cognitive function and underlying brain correlates in neurodegenerative diseases and high-workload environments.
Céline completed her PhD in Speech and Language Sciences in 2010 at the Laboratoire Parole et Langage, Aix-Marseille University. In her early postdoctoral research years, she investigated the speech characteristics of individuals with Parkinson’s disease and Multiple Sclerosis. In 2015, she received a Centre for Ageing Research and Development in Ireland grant to investigate the speech characteristics and underlying neural correlates of individuals with Mild Cognitive Impairment and Alzheimer’s disease.
Céline also lectured in the English Department and the Department of General Linguistics and Phonetics, at Aix-Marseille University and in the School of Linguistic, Speech and Communication Sciences and School of Engineering in TCD.
Céline has also been involved in research commercialisation projects. In 2012, she received an Entreprise Ireland Commercialisation Fund Program grant to develop a technology for the monitoring of airline pilots’ communication skills. She has been consultant for research and technology development for the starts-up Vocavio and Kids Speech Labs.
Peer-Reviewed Publications
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De Looze, Céline, Wilby Williamson, Rebecca Hirst, John O'Connor, Silvin Knight, Cathal McCrory, Daniel Carey, and Rose‐Anne Kenny. Impaired orthostatic heart rate recovery is associated with smaller thalamic volume: Results from The Irish Longitudinal Study on Aging (TILDA).. Human Brain Mapping (2020).
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De Looze, Céline, Finnian Kelly, Lisa Crosby, Aisling Vourdanou, Robert F. Coen, Cathal Walsh, Brian A. Lawlor, and Richard B. Reilly. Changes in speech chunking in reading aloud is a marker of mild cognitive impairment and mild-to-moderate Alzheimer's disease Current Alzheimer Research 15, no. 9 (2018): 828-847. Current Alzheimer Research 15 (2018)
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De Looze, Céline, Noémie Moreau Laurent Renié Finnian Kelly Alain Ghio Audrey Rico Bertrand Audoin François Viallet Jean Pelletier Caterina Petrone. Effects of cognitive impairment on prosodic parameters of speech production planning in multiple sclerosis. Journal of neuropsychology 13, no. 1 (2019): 22-45. Journal of neuropsychology
De Looze, Céline,Alan Beausang, Jane Cryan, Teresa Loftus, Patrick G. Buckley, Michael Farrell, Seamus Looby, Richard Reilly, Francesca Brett, and Hugh Kearney. Machine learning: a useful radiological adjunct in determination of a newly diagnosed glioma’s grade and IDH status. Journal of neuro-oncology 139, no. 2 (2018): 491-499.. Springer Online.