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Dr. Matthew O' Connell


Matthew O'ConnellMatthew O’Connell is a Beeson-CARDI Research Fellow. His undergraduate degree was in Sport and Exercise Sciences from the University of Birmingham. Following this, he completed a Ph.D. at the University of Manchester, graduating in 2011. His thesis was titled ‘Frailty and Anabolic Hormones in Ageing Men’, and involved work on the observational European Male Aging Study (EMAS) and a clinical trial of testosterone therapy in frail men. Matthew then undertook a post-doctoral contract in Manchester looking at longitudinal changes in sex hormone levels in the EMAS. He joined TILDA as a Research Fellow in January 2012 and worked for 3 years on projects related to frailty and physiological function in older adults. These included innovative work characterising the blood pressure response to orthostasis (standing up) at the population level, novel statistical approaches to age-related deficit accumulation and the first All-Ireland study on frailty. His Ph.D. and post-doctoral work has been published in leading journals including the Journal of Clinical Endocrinology and Metabolism, the Journal of the American Geriatrics Society and Circulation.

In 2015, he was awarded a Fellowship by the Centre for Ageing Research and Development in Ireland (CARDI) under their Leadership in Ageing Research programme, sponsored by the American Federation For Ageing Research Paul Beeson Career Development Awards for the Island of Ireland. The project ‘Novel Physiological Determinants of Functional Decline across Ireland’ aims to identify new markers of physiological dysregulation from detailed data on peripheral and central blood pressure behaviour collected in TILDA, and assess their relationship to decline in key functional domains like muscle strength and gait speed.  

Peer Reviewed Publications

Other Publications

  • Scarlett S, King Kallimanis BL, Young I, Kenny RA, O’Connell MDL. (2014) Frailty and Disability in Ireland. Report on main findings from datamining grant. Available from

  • Leahy S, Donoghue O, O'Connell M, O'Hare C, Nolan H. (2014) Obesity and Health Outcomes in Older Irish Adults, in The Over 50s in Changing Ireland: Economic Circumstances, Health and Wellbeing. First report on findings from wave 2 of the Irish Longitudinal study on Ageing

Research Grants

  • O’Connell MDL: Novel Physiological Determinants of Functional Decline Across Ireland. €229,246 - Ageing Research Leadership Fellowship from the Centre for Ageing Research and Development in Ireland sponsored by the American Federation for Ageing Research Beeson Awards 2015

  • O’Connell MDL, King-Kallimanis BL, Kenny RA: Frailty and Disability in Ireland. €15,214 - from the Centre for Ageing Research and Development in Ireland's second data-mining programme 2013

Last updated 24 November 2016 by TILDA - Web Administration (Email).